Intraoperative microwave processing of bone margins during resection of head and neck cancer.
نویسندگان
چکیده
OBJECTIVE To develop an accurate method for performing histopathologic analysis for a full cross-section of cortical bone within 2 to 3 hours. METHODS Microwave technology was used to augment and to more rapidly perform fixation and decalcification of cortical bone. RESULTS Using the methods described, slides suitable for histopathologic analyses regarding the presence or absence of malignant tumor were prepared in 2 to 3 hours and, in 10 patients studied, had a 100% correlation with slides prepared in 7 days using the standard decalcification technique. CONCLUSION Microwave technology allows accurate assessment of a full cross-section of cortical bone regarding the presence or absence of malignant tumor within the time limits required for resection of a malignant head and neck tumor and reconstruction of the surgical defect.
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ورودعنوان ژورنال:
- Archives of otolaryngology--head & neck surgery
دوره 127 7 شماره
صفحات -
تاریخ انتشار 2001